Compound research
TB-500: Research Overview & Current Status
TB-500 is a synthetic 7-amino-acid peptide fragment of thymosin beta-4. Current research status: preclinical research. TB-500 itself has not been studied in registered human clinical trials; the evidence base is predominantly preclinical, and most of the broader literature relates to full-length thymosin beta-4 (Tβ4) rather than the TB-500 fragment specifically.
Live vendor pricing
Showing 118 of 118 listings.
NextGen Peptides
Tracked$35.00 / 10mg($35.00 to 10mg)
Checked Jul 24, 2026
Check price at NextGen Peptides →Elite Edge Biotech
Tracked$38.00 / 10mg($38.00 to 10mg)
Checked Jul 28, 2026
Check price at Elite Edge Biotech →Noble Sciences
Tracked$39.00 / 10mg($39.00 to 10mg)
Checked Aug 1, 2026
Check price at Noble Sciences →Amino Club
Tracked$39.99 / 10mg($39.99 to 10mg)
Checked Aug 7, 2026
Check price at Amino Club →Woosh Labs
Tracked$39.99 / 10mg($39.99 to 10mg)
Checked Jun 24, 2026
Check price at Woosh Labs →Averix Labs
Tracked$39.99 / 10mg($39.99 to 10mg)
Checked Jul 16, 2026
Check price at Averix Labs →Everest Peptides
Tracked$39.99 / 10mg($39.99 to 10mg)
Checked Jul 28, 2026
Check price at Everest Peptides →VoidResearch
Tracked$39.99 / 10mg($39.99 to 10mg)
Checked Jul 30, 2026
Check price at VoidResearch →Pure Amino
Tracked$39.99 / 10mg($39.99 to 10mg)
Checked Aug 15, 2026
Check price at Pure Amino →Elytra Labs
Tracked$40.00 / 10mg($40.00 to 10mg)
Checked Aug 2, 2026
Check price at Elytra Labs →Badger Compounds
Tracked$41.99 / 10mg($41.99 to 10mg)
Checked Aug 15, 2026
Check price at Badger Compounds →Step One Ventures
Tracked$44.00 / 10mg($44.00 to 10mg)
Checked Jul 22, 2026
Check price at Step One Ventures →GMR Peptides
Tracked$44.99 / 10mg($44.99 to 10mg)
Checked Jul 29, 2026
Check price at GMR Peptides →RemedyX Labs
Tracked$45.00 / 10mg($45.00 to 10mg)
Checked Aug 1, 2026
Check price at RemedyX Labs →Peptide Giants
Tracked$49.49 / 10mg($49.49 to 10mg)
Checked Aug 1, 2026
Check price at Peptide Giants →Midwest Peptide
Tracked$49.99 / 10mg($49.99 to 10mg)
Checked Jun 18, 2026
Check price at Midwest Peptide →Ascend Amino
Tracked$49.99 / 10mg($49.99 to 10mg)
Checked Jul 28, 2026
Check price at Ascend Amino →Purgo Labs
Tracked$49.99 / 10mg($49.99 to 10mg)
Checked Aug 1, 2026
Check price at Purgo Labs →RUO Market
Tracked$49.99 / 10mg($49.99 to 10mg)
Checked Aug 2, 2026
Check price at RUO Market →Enhanced Chem
Tracked$49.99 / 10mg($49.99 to 10mg)
Checked Aug 15, 2026
Check price at Enhanced Chem →Premier Research
Tracked$50.00 / 10mg($50.00 to 10mg)
Checked Jul 20, 2026
Check price at Premier Research →Cielo Peptides
Tracked$50.00 / 10mg($50.00 to 10mg)
Checked Aug 8, 2026
Check price at Cielo Peptides →IDUN Peptides
Tracked$54.99 / 10mg($54.99 to 10mg)
Checked Jul 17, 2026
Check price at IDUN Peptides →Axon Chems
Tracked$55.00 / 10mg($55.00 to 10mg)
Checked Jul 31, 2026
Check price at Axon Chems →Offline Peptides
Tracked$55.00 / 10mg($55.00 to 10mg)
Checked Jul 28, 2026
Check price at Offline Peptides →Durham Peptides
Tracked$57.06 / 10mg($57.06 to 10mg)
Checked Aug 7, 2026
Check price at Durham Peptides →$58.65 / 10mg($58.65 to 10mg)
Checked Jul 31, 2026
Check price at Amino Vault →Glacier Aminos
Tracked$58.99 / 10mg($58.99 to 10mg)
Checked Jul 31, 2026
Check price at Glacier Aminos →PeakForce Labs
Tracked$59.00 / 10mg($59.00 to 10mg)
Checked Aug 15, 2026
Check price at PeakForce Labs →Apex Peptide Supply
Tracked$59.99 / 10mg($59.99 to 10mg)
Checked May 14, 2026
Check price at Apex Peptide Supply →SKO Compounds
Tracked$59.99 / 10mg($59.99 to 10mg)
Checked Jul 23, 2026
Check price at SKO Compounds →Orbitrex Peptides
Tracked$59.99 / 10mg($59.99 to 10mg)
Checked Aug 3, 2026
Check price at Orbitrex Peptides →Mile High Compounds
Tracked$59.99 / 10mg($59.99 to 10mg)
Checked Aug 3, 2026
Check price at Mile High Compounds →Nationwide Peptides
Tracked$62.00 / 10mg($62.00 to 10mg)
Checked Aug 5, 2026
Check price at Nationwide Peptides →NextGen Peptides
Tracked$64.00 / 20mg($64.00 to 10mg)
Checked Jul 24, 2026
Check price at NextGen Peptides →Purity Peptides
Tracked$64.09 / 10mg($64.09 to 10mg)
Checked Jul 16, 2026
Check price at Purity Peptides →Anglo Peptides
Tracked$32.10 / 5mg($64.20 to 10mg)
Checked Jul 19, 2026
Check price at Anglo Peptides →Ignite Peptides
Tracked$65.00 / 10mg($65.00 to 10mg)
Checked Jun 12, 2026
Check price at Ignite Peptides →Optima Supply
Tracked$65.00 / 10mg($65.00 to 10mg)
Checked Aug 3, 2026
Check price at Optima Supply →Atomik Labz
Tracked$65.00 / 10mg($65.00 to 10mg)
Checked Aug 4, 2026
Check price at Atomik Labz →Peptide Giants
Tracked$32.99 / 5mg($65.98 to 10mg)
Checked Aug 1, 2026
Check price at Peptide Giants →Global Aminos
Tracked$65.99 / 10mg($65.99 to 10mg)
Checked Jul 28, 2026
Check price at Global Aminos →EZ Peptides
Tracked$68.00 / 10mg($68.00 to 10mg)
Checked Aug 13, 2026
Check price at EZ Peptides →True Research Labs
Tracked$69.00 / 10mg($69.00 to 10mg)
Checked Aug 15, 2026
Check price at True Research Labs →Novatherix Laboratories
Tracked$69.99 / 10mg($69.99 to 10mg)
Checked Jun 4, 2026
Check price at Novatherix Laboratories →Axon Chems
Tracked$35.00 / 5mg($70.00 to 10mg)
Checked Jul 31, 2026
Check price at Axon Chems →Onyx Research
Tracked$70.00 / 10mg($70.00 to 10mg)
Checked Apr 6, 2026
Check price at Onyx Research →GLP-1 Research Lab
Tracked$70.00 / 10mg($70.00 to 10mg)
Checked Jun 19, 2026
Check price at GLP-1 Research Lab →PeakForm Peptides
Tracked$70.00 / 10mg($70.00 to 10mg)
Checked Aug 1, 2026
Check price at PeakForm Peptides →Polar Peptides
Tracked$71.99 / 10mg($71.99 to 10mg)
Checked Apr 17, 2026
Check price at Polar Peptides →Axiom Peptides
Tracked$36.00 / 5mg($72.00 to 10mg)
Checked Apr 14, 2026
Check price at Axiom Peptides →Chameleon Peptides
Tracked$72.90 / 10mg($72.90 to 10mg)
Checked Jul 31, 2026
Check price at Chameleon Peptides →Particle Peptides
Tracked$73.98 / 10mg($73.98 to 10mg)
Checked Jul 24, 2026
Check price at Particle Peptides →Offline Peptides
Tracked$37.00 / 5mg($74.00 to 10mg)
Checked Jul 28, 2026
Check price at Offline Peptides →Eternal Peptides
Tracked$74.99 / 10mg($74.99 to 10mg)
Checked Aug 2, 2026
Check price at Eternal Peptides →Enhanced Chem
Tracked$37.99 / 5mg($75.98 to 10mg)
Checked Aug 15, 2026
Check price at Enhanced Chem →Amino Science Labs
Tracked$75.99 / 10mg($75.99 to 10mg)
Checked Jul 27, 2026
Check price at Amino Science Labs →Modern Aminos
Tracked$38.00 / 5mg($76.00 to 10mg)
Checked May 14, 2026
Check price at Modern Aminos →Nationwide Peptides
Tracked$38.00 / 5mg($76.00 to 10mg)
Checked Aug 5, 2026
Check price at Nationwide Peptides →Apex Peptide Supply
Tracked$39.99 / 5mg($79.98 to 10mg)
Checked May 14, 2026
Check price at Apex Peptide Supply →Novatherix Laboratories
Tracked$39.99 / 5mg($79.98 to 10mg)
Checked Jun 4, 2026
Check price at Novatherix Laboratories →Euno Labs Research
Tracked$39.99 / 5mg($79.98 to 10mg)
Checked Jul 25, 2026
Check price at Euno Labs Research →Eternal Peptides
Tracked$39.99 / 5mg($79.98 to 10mg)
Checked Aug 2, 2026
Check price at Eternal Peptides →Arizen Bio Labs
Tracked$79.99 / 10mg($79.99 to 10mg)
Checked Jun 21, 2026
Check price at Arizen Bio Labs →Ignite Peptides
Tracked$40.00 / 5mg($80.00 to 10mg)
Checked Jun 12, 2026
Check price at Ignite Peptides →PeakForm Peptides
Tracked$40.00 / 5mg($80.00 to 10mg)
Checked Aug 1, 2026
Check price at PeakForm Peptides →Pristine Aminos
Tracked$80.00 / 10mg($80.00 to 10mg)
Checked Aug 2, 2026
Check price at Pristine Aminos →Swift Peptides
Tracked$43.99 / 5mg($87.98 to 10mg)
Checked Aug 6, 2026
Check price at Swift Peptides →Swift Peptides
Tracked$87.99 / 10mg($87.99 to 10mg)
Checked Aug 6, 2026
Check price at Swift Peptides →Perfect Peptides
Tracked$89.00 / 10mg($89.00 to 10mg)
Checked Jul 27, 2026
Check price at Perfect Peptides →Hydro Research
Tracked$90.00 / 10mg($90.00 to 10mg)
Checked Jun 5, 2026
Check price at Hydro Research →Chameleon Peptides
Tracked$46.80 / 5mg($93.60 to 10mg)
Checked Jul 31, 2026
Check price at Chameleon Peptides →Apex Peptides Lab
Tracked$99.00 / 10mg($99.00 to 10mg)
Checked Aug 15, 2026
Check price at Apex Peptides Lab →Licensed Peptides
Tracked$99.99 / 10mg($99.99 to 10mg)
Checked Jun 4, 2026
Check price at Licensed Peptides →$50.00 / 5mg($100.00 to 10mg)
Checked Apr 16, 2026
Check price at Ascension Peptides →CertaPeptides
Tracked$50.68 / 5mg($101.36 to 10mg)
Checked Jun 27, 2026
Check price at CertaPeptides →CertaPeptides
Tracked$102.52 / 10mg($102.52 to 10mg)
Checked Jun 27, 2026
Check price at CertaPeptides →Purity Peptides
Tracked$51.70 / 5mg($103.40 to 10mg)
Checked Jul 16, 2026
Check price at Purity Peptides →BioPure Peptides
Tracked$104.99 / 10mg($104.99 to 10mg)
Checked Jul 27, 2026
Check price at BioPure Peptides →UNYX Peptides
Tracked$109.99 / 10mg($109.99 to 10mg)
Checked Jul 31, 2026
Check price at UNYX Peptides →Vantyx Research
Tracked$55.00 / 5mg($110.00 to 10mg)
Checked Aug 15, 2026
Check price at Vantyx Research →Hydro Research
Tracked$55.00 / 5mg($110.00 to 10mg)
Checked Jun 5, 2026
Check price at Hydro Research →Liv Pure Wellness
Tracked$110.00 / 10mg($110.00 to 10mg)
Checked Apr 14, 2026
Check price at Liv Pure Wellness →UNYX Peptides
Tracked$59.99 / 5mg($119.98 to 10mg)
Checked Jul 31, 2026
Check price at UNYX Peptides →Liv Pure Wellness
Tracked$67.00 / 5mg($134.00 to 10mg)
Checked Apr 14, 2026
Check price at Liv Pure Wellness →Apex Peptides Lab
Tracked$69.00 / 5mg($138.00 to 10mg)
Checked Aug 15, 2026
Check price at Apex Peptides Lab →$140.00 / 10mg($140.00 to 10mg)
Checked Apr 16, 2026
Check price at Core Peptides →Atomik Labz
Tracked$140.00 / 20mg($140.00 to 10mg)
Checked Aug 4, 2026
Check price at Atomik Labz →Polar Peptides
Tracked$140.39 / 20mg($140.39 to 10mg)
Checked Apr 17, 2026
Check price at Polar Peptides →Apex Peptide Supply
Tracked$29.99 / 2mg($149.95 to 10mg)
Checked May 14, 2026
Check price at Apex Peptide Supply →$78.00 / 5mg($156.00 to 10mg)
Checked Apr 16, 2026
Check price at Core Peptides →BioLongevity Labs
Tracked$164.97 / 10mg($164.97 to 10mg)
Checked Aug 2, 2026
Check price at BioLongevity Labs →CertaPeptides
Tracked$35.87 / 2mg($179.35 to 10mg)
Checked Jun 27, 2026
Check price at CertaPeptides →PureBio Labs
Tracked$89.99 / 5mg($179.98 to 10mg)
Checked Aug 5, 2026
Check price at PureBio Labs →CertaPeptides
Tracked$186.25 / 20mg($186.25 to 10mg)
Checked Jun 27, 2026
Check price at CertaPeptides →Pepsynth Labs
Tracked$135.00 / 5mg($270.00 to 10mg)
Checked Aug 7, 2026
Check price at Pepsynth Labs →Peptides For Less
Tracked$25.00 / 10mg($25.00 to 10mg)
Checked Aug 13, 2026
Check price at Peptides For Less →Peptides For Less
Tracked$15.00 / 5mg($30.00 to 10mg)
Checked Aug 13, 2026
Check price at Peptides For Less →Alpha Peptides
Tracked$31.32 / 10mg($31.32 to 10mg)
Checked Jul 31, 2026
Check price at Alpha Peptides →TB-500 price report
TB-500 currently costs as little as $25.00 to obtain 10mg, from Peptides For Less. Across the 88 vendors we track, the typical cost to 10mg is $64.09, using each vendor's own cheapest listing. 86 of those vendors show current stock, and prices were checked through Aug 15, 2026.
- Lowest to 10mg
- $25.00
- Peptides For Less
- Median to 10mg
- $64.09
- one offer per vendor
- Lowest package
- $29.99
- 5mg at MsAmino
- Vendors tracked
- 88
- 86 in stock
Checked through Aug 15, 2026. Prices are aggregated from public vendor listings. Sources and data licensing are documented on our methodology page.
At a glance
- Category
- recovery
- Mechanism class
- Thymic / immune modulator
- Research phase
- Research / preclinical only
- NCAA status
- Banned (NCAA 2025-26 list) — Explicitly named on NCAA Banned Drugs List under Peptide Hormones, Growth Factors & Mimetics.
- WADA status
- Prohibited (WADA S2 — Peptide Hormones, Growth Factors, Related Substances)
Overview
TB-500 is a synthetic fragment (Ac-LKKTETQ) corresponding to the actin-binding domain (residues 17-23) of thymosin beta-4 (Tβ4), a naturally occurring 43-amino-acid protein involved in actin regulation and cell migration. It was developed as a shorter, more stable, easier-to-characterize alternative to full-length Tβ4 for research purposes.
synthetic 7-amino-acid peptide fragment of thymosin beta-4
Research timeline
1999
Foundational study in the Journal of Investigative Dermatology reporting that topical/intraperitoneal Tβ4 increased reepithelialization by up to 61% by day 7 in a rat full-thickness dermal wound model.
Source →2000s
Expansion of Tβ4/TB-500 research into skeletal muscle injury, cardiac tissue (post-ischemic models), neurological/spinal cord injury models, and corneal wound healing in animal studies.
Source →2024
Metabolism research (Rahaman et al.) reported that TB-500's wound-healing activity may stem from a metabolite, Ac-LKKTE, rather than the parent fragment itself.
Source →2026
A scoping review in Applied Sciences (MDPI) mapped the Tβ4/TB-500 tissue-repair literature and found direct TB-500 evidence for musculoskeletal applications limited to a single included study.
Source →
Active & recent research
Thymosin Beta-4 and TB-500 in Tissue Healing, Regeneration, and Musculoskeletal Repair: A Scoping Review
mapping the tendon, ligament, muscle, cartilage, and spine/intervertebral disc literature for Tβ4 and TB-500
Achilles tendon injury model research
tendon strength and collagen organization (type I collagen remodeling) following Tβ4 administration
TB-500 metabolite research
identification of Ac-LKKTE as an active metabolite potentially responsible for wound-healing activity attributed to TB-500
Key findings
- A 1999 rat dermal wound study reported that thymosin beta-4 increased reepithelialization by 42% at day 4 and 61% at day 7 versus saline controls, with increased collagen deposition and angiogenesis.
- Rat Achilles tendon injury studies reported statistically significant improvements in tendon strength and collagen organization in Tβ4-treated animals compared to controls.
- A 2026 scoping review found the musculoskeletal-specific literature for TB-500 (as opposed to full Tβ4) to be sparse, with direct TB-500 evidence limited to a single included study, and concluded the overall evidence base remains largely preclinical with limited human relevance.
- 2024 metabolism research suggested a metabolite of TB-500 (Ac-LKKTE) rather than the intact fragment may drive observed wound-healing effects, an open mechanistic question in the field.
Safety & regulatory notes
TB-500 is not FDA-approved for any human use and has not been evaluated in registered human clinical trials; no standardized human safety or dosing data exist. It is sold only as a research chemical. Growth factor/peptide compounds in this general class are subject to WADA's S2 prohibited category for competitive athletes, so individuals subject to anti-doping testing should assume it is prohibited.
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Where it's sold for research
We track vendor availability and published pricing for TB-500 on a dedicated page. See where to buy TB-500 →
TB-500 FAQ
Is TB-500 FDA-approved?+
No. TB-500 has no FDA approval and has not been evaluated in registered human clinical trials.
What is TB-500 studied for?+
Preclinical (largely rodent) research has examined thymosin beta-4 and the TB-500 fragment in models of dermal wound healing, tendon repair, cardiac and corneal tissue, and skeletal muscle injury.
Is TB-500 the same as thymosin beta-4?+
No. TB-500 is a short synthetic fragment representing thymosin beta-4's actin-binding domain, not the full 43-amino-acid protein; most published wound-healing literature is on full-length Tβ4, and a 2026 scoping review found direct TB-500-specific evidence to be limited.
Is TB-500 legal to buy for research purposes?+
It is sold by some suppliers as a research chemical labeled not for human consumption; it has no approved therapeutic use and buyers should understand its unregulated status.
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Researched together
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