Compound research
Sermorelin: Research Overview & Current Status
Sermorelin is a GHRH analog (growth hormone secretagogue). Current research status: approved (non-drug / other indication). Sermorelin acetate was FDA-approved in the U.S. under the brand name Geref for diagnostic and pediatric growth hormone deficiency use, though the original branded product was later discontinued from the U.S. market for commercial reasons; sermorelin is now primarily available via compounding pharmacies and is studied off-label in adult and aging populations.
Live vendor pricing
Showing 70 of 70 listings.
Noble Sciences
Tracked$39.00 / 10mg($39.00 to 10mg)
Checked Aug 1, 2026
Check price at Noble Sciences →Cielo Peptides
Tracked$40.00 / 10mg($40.00 to 10mg)
Checked Aug 8, 2026
Check price at Cielo Peptides →NextGen Peptides
Tracked$45.00 / 10mg($45.00 to 10mg)
Checked Jul 24, 2026
Check price at NextGen Peptides →Orbitrex Peptides
Tracked$49.99 / 10mg($49.99 to 10mg)
Checked Aug 3, 2026
Check price at Orbitrex Peptides →RUO Market
Tracked$54.99 / 10mg($54.99 to 10mg)
Checked Aug 2, 2026
Check price at RUO Market →Nationwide Peptides
Tracked$59.00 / 10mg($59.00 to 10mg)
Checked Aug 5, 2026
Check price at Nationwide Peptides →Chameleon Peptides
Tracked$61.20 / 10mg($61.20 to 10mg)
Checked Jul 31, 2026
Check price at Chameleon Peptides →Glacier Aminos
Tracked$62.99 / 10mg($62.99 to 10mg)
Checked Jul 31, 2026
Check price at Glacier Aminos →Badger Compounds
Tracked$31.99 / 5mg($63.98 to 10mg)
Checked Aug 15, 2026
Check price at Badger Compounds →Hydro Research
Tracked$64.00 / 10mg($64.00 to 10mg)
Checked Jun 5, 2026
Check price at Hydro Research →Optima Supply
Tracked$64.00 / 10mg($64.00 to 10mg)
Checked Aug 3, 2026
Check price at Optima Supply →Atomik Labz
Tracked$64.00 / 10mg($64.00 to 10mg)
Checked Aug 4, 2026
Check price at Atomik Labz →Purity Peptides
Tracked$64.09 / 10mg($64.09 to 10mg)
Checked Jul 16, 2026
Check price at Purity Peptides →Premier Research
Tracked$65.00 / 10mg($65.00 to 10mg)
Checked Jul 20, 2026
Check price at Premier Research →Axon Chems
Tracked$65.00 / 10mg($65.00 to 10mg)
Checked Jul 31, 2026
Check price at Axon Chems →PeakForce Labs
Tracked$69.00 / 10mg($69.00 to 10mg)
Checked Aug 15, 2026
Check price at PeakForce Labs →True Research Labs
Tracked$69.00 / 10mg($69.00 to 10mg)
Checked Aug 15, 2026
Check price at True Research Labs →Mile High Compounds
Tracked$69.99 / 10mg($69.99 to 10mg)
Checked Aug 3, 2026
Check price at Mile High Compounds →Rivn Peptides
Tracked$69.99 / 10mg($69.99 to 10mg)
Checked Aug 14, 2026
Check price at Rivn Peptides →PeakForm Peptides
Tracked$70.00 / 10mg($70.00 to 10mg)
Checked Aug 1, 2026
Check price at PeakForm Peptides →CertaPeptides
Tracked$35.30 / 5mg($70.60 to 10mg)
Checked Jun 27, 2026
Check price at CertaPeptides →Eternal Peptides
Tracked$74.99 / 10mg($74.99 to 10mg)
Checked Aug 2, 2026
Check price at Eternal Peptides →Evolve Peptides
Tracked$75.00 / 10mg($75.00 to 10mg)
Checked Apr 22, 2026
Check price at Evolve Peptides →Pristine Aminos
Tracked$75.00 / 10mg($75.00 to 10mg)
Checked Aug 2, 2026
Check price at Pristine Aminos →Anglo Peptides
Tracked$38.53 / 5mg($77.06 to 10mg)
Checked Jul 19, 2026
Check price at Anglo Peptides →Nationwide Peptides
Tracked$39.00 / 5mg($78.00 to 10mg)
Checked Aug 5, 2026
Check price at Nationwide Peptides →Apex Peptides Lab
Tracked$79.00 / 10mg($79.00 to 10mg)
Checked Aug 15, 2026
Check price at Apex Peptides Lab →Chameleon Peptides
Tracked$39.60 / 5mg($79.20 to 10mg)
Checked Jul 31, 2026
Check price at Chameleon Peptides →CertaPeptides
Tracked$15.94 / 2mg($79.70 to 10mg)
Checked Jun 27, 2026
Check price at CertaPeptides →Apex Peptide Supply
Tracked$39.99 / 5mg($79.98 to 10mg)
Checked May 14, 2026
Check price at Apex Peptide Supply →Eternal Peptides
Tracked$39.99 / 5mg($79.98 to 10mg)
Checked Aug 2, 2026
Check price at Eternal Peptides →Enhanced Chem
Tracked$39.99 / 5mg($79.98 to 10mg)
Checked Aug 15, 2026
Check price at Enhanced Chem →PeakForm Peptides
Tracked$40.00 / 5mg($80.00 to 10mg)
Checked Aug 1, 2026
Check price at PeakForm Peptides →Liv Pure Wellness
Tracked$85.00 / 10mg($85.00 to 10mg)
Checked Apr 14, 2026
Check price at Liv Pure Wellness →$85.00 / 10mg($85.00 to 10mg)
Checked Apr 16, 2026
Check price at Ascension Peptides →Purity Peptides
Tracked$42.72 / 5mg($85.44 to 10mg)
Checked Jul 16, 2026
Check price at Purity Peptides →$43.00 / 5mg($86.00 to 10mg)
Checked May 14, 2026
Check price at Biotech Peptides →Swift Peptides
Tracked$43.99 / 5mg($87.98 to 10mg)
Checked Aug 6, 2026
Check price at Swift Peptides →Offline Peptides
Tracked$44.00 / 5mg($88.00 to 10mg)
Checked Jul 28, 2026
Check price at Offline Peptides →EZ Peptides
Tracked$44.00 / 5mg($88.00 to 10mg)
Checked Aug 13, 2026
Check price at EZ Peptides →Olympex Solutions
Tracked$44.98 / 5mg($89.96 to 10mg)
Checked Apr 6, 2026
Check price at Olympex Solutions →Evolve Peptides
Tracked$45.00 / 5mg($90.00 to 10mg)
Checked Apr 22, 2026
Check price at Evolve Peptides →Axon Chems
Tracked$45.00 / 5mg($90.00 to 10mg)
Checked Jul 31, 2026
Check price at Axon Chems →Modern Aminos
Tracked$48.00 / 5mg($96.00 to 10mg)
Checked May 14, 2026
Check price at Modern Aminos →$48.00 / 5mg($96.00 to 10mg)
Checked Apr 16, 2026
Check price at Core Peptides →$49.73 / 5mg($99.46 to 10mg)
Checked Jul 31, 2026
Check price at Amino Vault →Onyx Research
Tracked$50.00 / 5mg($100.00 to 10mg)
Checked Apr 6, 2026
Check price at Onyx Research →Ignite Peptides
Tracked$50.00 / 5mg($100.00 to 10mg)
Checked Jun 12, 2026
Check price at Ignite Peptides →UNYX Peptides
Tracked$100.00 / 10mg($100.00 to 10mg)
Checked Jul 31, 2026
Check price at UNYX Peptides →Pantheon Peptides
Tracked$50.40 / 5mg($100.80 to 10mg)
Checked Apr 23, 2026
Check price at Pantheon Peptides →Dynotides
Tracked$108.00 / 10mg($108.00 to 10mg)
Checked Jul 20, 2026
Check price at Dynotides →UNYX Peptides
Tracked$55.00 / 5mg($110.00 to 10mg)
Checked Jul 31, 2026
Check price at UNYX Peptides →Licensed Peptides
Tracked$114.99 / 10mg($114.99 to 10mg)
Checked Jun 4, 2026
Check price at Licensed Peptides →Apex Peptides
Tracked$125.00 / 10mg($125.00 to 10mg)
Checked Jul 31, 2026
Check price at Apex Peptides →PureBio Labs
Tracked$128.00 / 10mg($128.00 to 10mg)
Checked Aug 5, 2026
Check price at PureBio Labs →Pantheon Peptides
Tracked$28.80 / 2mg($144.00 to 10mg)
Checked Apr 23, 2026
Check price at Pantheon Peptides →$160.65 / 10mg($160.65 to 10mg)
Checked Jul 31, 2026
Check price at Amino Vault →SKO Compounds
Tracked$99.99 / 5mg($199.98 to 10mg)
Checked Jul 23, 2026
Check price at SKO Compounds →Alpha Peptides
Tracked$44.53 / 10mg($44.53 to 10mg)
Checked Jul 31, 2026
Check price at Alpha Peptides →CertaPeptides
Tracked$67.20 / 10mg($67.20 to 10mg)
Checked Jun 27, 2026
Check price at CertaPeptides →Arizen Bio Labs
Tracked$74.99 / 10mg($74.99 to 10mg)
Checked Jun 21, 2026
Check price at Arizen Bio Labs →Sermorelin price report
Sermorelin currently costs as little as $35.00 to obtain 10mg, from AmiNexa. Across the 57 vendors we track, the typical cost to 10mg is $75.00, using each vendor's own cheapest listing. 55 of those vendors show current stock, and prices were checked through Aug 15, 2026.
- Lowest to 10mg
- $35.00
- AmiNexa
- Median to 10mg
- $75.00
- one offer per vendor
- Lowest package
- $15.94
- 2mg at CertaPeptides
- Vendors tracked
- 57
- 55 in stock
Checked through Aug 15, 2026. Prices are aggregated from public vendor listings. Sources and data licensing are documented on our methodology page.
At a glance
- Category
- fat loss
- Mechanism class
- Growth hormone secretagogue (GHRH analog)
- Research phase
- FDA approved (for specific indications)
- NCAA status
- Banned (NCAA 2025-26 list) — GHRH analog (first 29 aa); WADA S2.2.4 explicitly lists sermorelin. Banned under NCAA catchall.
- WADA status
- Prohibited (WADA S2 — Peptide Hormones, Growth Factors, Related Substances)
Overview
Sermorelin is a synthetic 29-amino-acid fragment of human growth hormone-releasing hormone (GHRH), representing the shortest fragment that retains full biological activity of the native hormone. It acts on GHRH receptors in the anterior pituitary to stimulate endogenous growth hormone release, rather than supplying growth hormone directly.
GHRH analog (growth hormone secretagogue)
Research timeline
1980s
GHRH(1-29) fragment identified as the minimal peptide sequence retaining full GH-releasing bioactivity of native GHRH.
Source →1990s
Sermorelin acetate (Geref) approved by FDA for diagnostic testing and treatment of pediatric growth hormone deficiency.
Source →1997
Corpas et al. trial in older men showed short-term GHRH administration could restore GH and IGF-1 levels toward those seen in younger men.
Source →1990s-2000s
Khorram et al. 5-month randomized placebo-controlled trial in adults aged 55-71 reported significant increases in nocturnal GH and serum IGF-1.
Source →2007
PubMed review concluded sermorelin is well-tolerated as a provocative diagnostic test for GH deficiency and modestly effective in promoting growth in some prepubertal children with idiopathic GHD.
Source →2021
Analytical chemistry study developed LC-MS/MS methods to detect sermorelin and related GHRH analogs (tesamorelin, CJC-1295) in urine for anti-doping purposes.
Source →
Active & recent research
Diagnostic use of sermorelin as a provocative test for growth hormone deficiency in children
Evaluating sermorelin injection as a specific, low-false-positive diagnostic stimulation test versus other GH provocation tests
GHRH/sermorelin administration in aging adults
Effect on nocturnal GH pulsatility and serum IGF-1 in age-related GH decline
Detection of GHRH synthetic analogs in sport anti-doping contexts
Identifying metabolites of sermorelin, tesamorelin, and CJC-1295 for analytical detection
Key findings
- A PubMed review reported that intravenous sermorelin (1 mcg/kg) functions as a rapid, relatively specific provocative test for growth hormone deficiency in children, with fewer false positives than some alternative tests.
- A randomized placebo-controlled trial in older adults (Khorram et al.) reported significant increases in nocturnal GH and IGF-1 after GHRH-analog administration in both men and women.
- Preliminary pediatric data cited in a 2007 review suggested continued GH-release and growth-velocity effects with sermorelin treatment tracked up to 36 months, though long-term controlled data remain limited.
- Because sermorelin stimulates endogenous GH release (regulated by feedback via somatostatin) rather than supplying GH directly, researchers have noted it may carry a different overdose/safety profile than exogenous recombinant GH. This is a mechanistic hypothesis discussed in the literature, not a clinical guarantee.
Safety & regulatory notes
Sermorelin acetate (Geref) previously held FDA approval for pediatric GHD diagnosis/treatment; the branded product has since been discontinued in the U.S. market, and current supply is largely through compounding pharmacies, which changes its regulatory status. Reported adverse effects in trials include injection-site reactions, flushing, and headache. Long-term safety data in healthy adult 'anti-aging' or off-label use populations are limited compared to the pediatric diagnostic literature.
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Where it's sold for research
We haven't built a dedicated vendor-availability page for Sermorelin yet. See our full research-peptide vendor rankings →
Sermorelin FAQ
Is sermorelin FDA-approved?+
A sermorelin acetate product (Geref) was previously FDA-approved for pediatric growth hormone deficiency diagnosis and treatment, but the branded product is no longer marketed in the U.S.; current use is largely via compounded formulations, which are regulated differently than an approved drug.
What has research shown about sermorelin in older adults?+
Small trials, such as a 5-month randomized placebo-controlled study by Khorram et al., reported increases in nocturnal GH and IGF-1 levels in adults aged 55-71, but sample sizes were small and this is not an FDA-approved indication.
How does sermorelin differ mechanistically from growth hormone itself?+
Sermorelin is a GHRH receptor agonist that stimulates the pituitary to release the body's own growth hormone, rather than being growth hormone itself; researchers have hypothesized this preserves normal feedback regulation, though this has not been established as a clinical safety guarantee.
Has sermorelin been studied for anti-doping detection?+
Yes. Analytical chemistry studies have developed LC-MS/MS methods to detect sermorelin and related GHRH analogs in urine, reflecting its inclusion in sports anti-doping monitoring frameworks.
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Researched together
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