Compound research
Semaglutide: Research Overview & Current Status
Semaglutide is a GLP-1 receptor agonist. Current research status: fda-approved. Semaglutide is FDA-approved under three brand names for distinct indications: Ozempic (type 2 diabetes, cardiovascular/kidney risk reduction), Rybelsus (oral, type 2 diabetes), and Wegovy (chronic weight management, cardiovascular risk reduction in adults with obesity/overweight and established cardiovascular disease, and MASH under accelerated approval). Compounded (non-brand) semaglutide is not FDA-approved and is subject to active FDA enforcement.
Live vendor pricing
Showing 136 of 136 listings.
Red River Peptides
Tracked$20.00 / 10mg($20.00 to 10mg)
Checked May 19, 2026
Check price at Red River Peptides →Red River Peptides
Tracked$30.00 / 20mg($30.00 to 10mg)
Checked May 19, 2026
Check price at Red River Peptides →Puratek Peptides
Tracked$34.95 / 10mg($34.95 to 10mg)
Checked Jul 31, 2026
Check price at Puratek Peptides →Vantyx Research
Tracked$35.00 / 10mg($35.00 to 10mg)
Checked Aug 15, 2026
Check price at Vantyx Research →Step One Ventures
Tracked$38.00 / 10mg($38.00 to 10mg)
Checked Jul 22, 2026
Check price at Step One Ventures →Elite Edge Biotech
Tracked$38.00 / 10mg($38.00 to 10mg)
Checked Jul 28, 2026
Check price at Elite Edge Biotech →Noble Sciences
Tracked$39.00 / 10mg($39.00 to 10mg)
Checked Aug 1, 2026
Check price at Noble Sciences →Step One Ventures
Tracked$20.00 / 5mg($40.00 to 10mg)
Checked Jul 22, 2026
Check price at Step One Ventures →Premier Research
Tracked$40.00 / 10mg($40.00 to 10mg)
Checked Jul 20, 2026
Check price at Premier Research →True Research Labs
Tracked$44.00 / 10mg($44.00 to 10mg)
Checked Aug 15, 2026
Check price at True Research Labs →Badger Compounds
Tracked$44.99 / 10mg($44.99 to 10mg)
Checked Aug 15, 2026
Check price at Badger Compounds →Durham Peptides
Tracked$46.36 / 10mg($46.36 to 10mg)
Checked Aug 7, 2026
Check price at Durham Peptides →EZ Peptides
Tracked$48.00 / 10mg($48.00 to 10mg)
Checked Aug 13, 2026
Check price at EZ Peptides →Peptide Giants
Tracked$49.49 / 10mg($49.49 to 10mg)
Checked Aug 1, 2026
Check price at Peptide Giants →Arizen Bio Labs
Tracked$49.99 / 10mg($49.99 to 10mg)
Checked Jun 21, 2026
Check price at Arizen Bio Labs →Purgo Labs
Tracked$49.99 / 10mg($49.99 to 10mg)
Checked Aug 1, 2026
Check price at Purgo Labs →Axon Chems
Tracked$50.00 / 15mg($50.00 to 10mg)
Checked Jul 31, 2026
Check price at Axon Chems →PeakForm Peptides
Tracked$50.00 / 10mg($50.00 to 10mg)
Checked Aug 1, 2026
Check price at PeakForm Peptides →Anglo Peptides
Tracked$54.23 / 10mg($54.23 to 10mg)
Checked Jul 19, 2026
Check price at Anglo Peptides →Step One Ventures
Tracked$55.00 / 30mg($55.00 to 10mg)
Checked Jul 22, 2026
Check price at Step One Ventures →Offline Peptides
Tracked$55.00 / 10mg($55.00 to 10mg)
Checked Jul 28, 2026
Check price at Offline Peptides →GLP-1 Research Lab
Tracked$57.50 / 10mg($57.50 to 10mg)
Checked Jun 19, 2026
Check price at GLP-1 Research Lab →CertaPeptides
Tracked$57.52 / 10mg($57.52 to 10mg)
Checked Jun 27, 2026
Check price at CertaPeptides →Novatherix Laboratories
Tracked$59.99 / 10mg($59.99 to 10mg)
Checked Jun 4, 2026
Check price at Novatherix Laboratories →RUO Market
Tracked$59.99 / 10mg($59.99 to 10mg)
Checked Aug 2, 2026
Check price at RUO Market →Elite Edge Biotech
Tracked$30.00 / 5mg($60.00 to 10mg)
Checked Jul 28, 2026
Check price at Elite Edge Biotech →Ascend Amino
Tracked$60.00 / 10mg($60.00 to 10mg)
Checked Jul 28, 2026
Check price at Ascend Amino →Cielo Peptides
Tracked$60.00 / 10mg($60.00 to 10mg)
Checked Aug 8, 2026
Check price at Cielo Peptides →Amino Science Labs
Tracked$60.99 / 10mg($60.99 to 10mg)
Checked Jul 27, 2026
Check price at Amino Science Labs →True Research Labs
Tracked$64.00 / 20mg($64.00 to 10mg)
Checked Aug 15, 2026
Check price at True Research Labs →Anglo Peptides
Tracked$32.10 / 5mg($64.20 to 10mg)
Checked Jul 19, 2026
Check price at Anglo Peptides →Badger Compounds
Tracked$64.99 / 20mg($64.99 to 10mg)
Checked Aug 15, 2026
Check price at Badger Compounds →Peptide Giants
Tracked$32.99 / 5mg($65.98 to 10mg)
Checked Aug 1, 2026
Check price at Peptide Giants →Nationwide Peptides
Tracked$68.00 / 10mg($68.00 to 10mg)
Checked Aug 5, 2026
Check price at Nationwide Peptides →CertaPeptides
Tracked$34.16 / 5mg($68.32 to 10mg)
Checked Jun 27, 2026
Check price at CertaPeptides →CertaPeptides
Tracked$68.34 / 15mg($68.34 to 10mg)
Checked Jun 27, 2026
Check price at CertaPeptides →PeakForce Labs
Tracked$69.00 / 10mg($69.00 to 10mg)
Checked Aug 15, 2026
Check price at PeakForce Labs →Eternal Peptides
Tracked$69.99 / 10mg($69.99 to 10mg)
Checked Aug 2, 2026
Check price at Eternal Peptides →Mile High Compounds
Tracked$69.99 / 10mg($69.99 to 10mg)
Checked Aug 3, 2026
Check price at Mile High Compounds →Axon Chems
Tracked$35.00 / 5mg($70.00 to 10mg)
Checked Jul 31, 2026
Check price at Axon Chems →EZ Peptides
Tracked$35.00 / 5mg($70.00 to 10mg)
Checked Aug 13, 2026
Check price at EZ Peptides →Premier Research
Tracked$70.00 / 20mg($70.00 to 10mg)
Checked Jul 20, 2026
Check price at Premier Research →Axon Chems
Tracked$70.00 / 20mg($70.00 to 10mg)
Checked Jul 31, 2026
Check price at Axon Chems →Glacier Aminos
Tracked$71.99 / 15mg($71.99 to 10mg)
Checked Jul 31, 2026
Check price at Glacier Aminos →Anglo Peptides
Tracked$74.92 / 20mg($74.92 to 10mg)
Checked Jul 19, 2026
Check price at Anglo Peptides →Amino Science Labs
Tracked$74.99 / 20mg($74.99 to 10mg)
Checked Jul 27, 2026
Check price at Amino Science Labs →Apex Peptides
Tracked$75.00 / 10mg($75.00 to 10mg)
Checked Jul 31, 2026
Check price at Apex Peptides →Chameleon Peptides
Tracked$76.50 / 10mg($76.50 to 10mg)
Checked Jul 31, 2026
Check price at Chameleon Peptides →$79.05 / 10mg($79.05 to 10mg)
Checked Jul 31, 2026
Check price at Amino Vault →CertaPeptides
Tracked$79.73 / 20mg($79.73 to 10mg)
Checked Jun 27, 2026
Check price at CertaPeptides →Novatherix Laboratories
Tracked$39.99 / 5mg($79.98 to 10mg)
Checked Jun 4, 2026
Check price at Novatherix Laboratories →Arizen Bio Labs
Tracked$39.99 / 5mg($79.98 to 10mg)
Checked Jun 21, 2026
Check price at Arizen Bio Labs →Eternal Peptides
Tracked$39.99 / 5mg($79.98 to 10mg)
Checked Aug 2, 2026
Check price at Eternal Peptides →Evo Labs Research
Tracked$79.99 / 10mg($79.99 to 10mg)
Checked Jun 22, 2026
Check price at Evo Labs Research →UNYX Peptides
Tracked$79.99 / 10mg($79.99 to 10mg)
Checked Jul 31, 2026
Check price at UNYX Peptides →Orbitrex Peptides
Tracked$79.99 / 10mg($79.99 to 10mg)
Checked Aug 3, 2026
Check price at Orbitrex Peptides →Rivn Peptides
Tracked$79.99 / 10mg($79.99 to 10mg)
Checked Aug 14, 2026
Check price at Rivn Peptides →Amino Science Labs
Tracked$41.99 / 5mg($83.98 to 10mg)
Checked Jul 27, 2026
Check price at Amino Science Labs →True Research Labs
Tracked$84.00 / 30mg($84.00 to 10mg)
Checked Aug 15, 2026
Check price at True Research Labs →Offline Peptides
Tracked$89.00 / 20mg($89.00 to 10mg)
Checked Jul 28, 2026
Check price at Offline Peptides →Pinnacle Peptide Labs
Tracked$89.99 / 10mg($89.99 to 10mg)
Checked Jul 22, 2026
Check price at Pinnacle Peptide Labs →Novatherix Laboratories
Tracked$89.99 / 20mg($89.99 to 10mg)
Checked Jun 4, 2026
Check price at Novatherix Laboratories →Arizen Bio Labs
Tracked$89.99 / 20mg($89.99 to 10mg)
Checked Jun 21, 2026
Check price at Arizen Bio Labs →Woosh Labs
Tracked$89.99 / 10mg($89.99 to 10mg)
Checked Jun 24, 2026
Check price at Woosh Labs →Nationwide Peptides
Tracked$92.00 / 20mg($92.00 to 10mg)
Checked Aug 5, 2026
Check price at Nationwide Peptides →Nationwide Peptides
Tracked$48.00 / 5mg($96.00 to 10mg)
Checked Aug 5, 2026
Check price at Nationwide Peptides →Atomik Labz
Tracked$99.00 / 10mg($99.00 to 10mg)
Checked Aug 4, 2026
Check price at Atomik Labz →Evo Labs Research
Tracked$49.99 / 5mg($99.98 to 10mg)
Checked Jun 22, 2026
Check price at Evo Labs Research →Evo Labs Research
Tracked$99.99 / 15mg($99.99 to 10mg)
Checked Jun 22, 2026
Check price at Evo Labs Research →Global Aminos
Tracked$99.99 / 10mg($99.99 to 10mg)
Checked Jul 28, 2026
Check price at Global Aminos →Rivn Peptides
Tracked$99.99 / 20mg($99.99 to 10mg)
Checked Aug 14, 2026
Check price at Rivn Peptides →Hydro Research
Tracked$100.00 / 10mg($100.00 to 10mg)
Checked Jun 5, 2026
Check price at Hydro Research →Premier Research
Tracked$100.00 / 30mg($100.00 to 10mg)
Checked Jul 20, 2026
Check price at Premier Research →Axon Chems
Tracked$100.00 / 30mg($100.00 to 10mg)
Checked Jul 31, 2026
Check price at Axon Chems →Apex Peptides
Tracked$100.00 / 20mg($100.00 to 10mg)
Checked Jul 31, 2026
Check price at Apex Peptides →Optima Supply
Tracked$109.99 / 10mg($109.99 to 10mg)
Checked Aug 3, 2026
Check price at Optima Supply →UNYX Peptides
Tracked$109.99 / 15mg($109.99 to 10mg)
Checked Jul 31, 2026
Check price at UNYX Peptides →Purgo Labs
Tracked$109.99 / 20mg($109.99 to 10mg)
Checked Aug 1, 2026
Check price at Purgo Labs →CertaPeptides
Tracked$22.20 / 2mg($111.00 to 10mg)
Checked Jun 27, 2026
Check price at CertaPeptides →Midwest Peptide
Tracked$111.99 / 20mg($111.99 to 10mg)
Checked Jun 18, 2026
Check price at Midwest Peptide →Apex Peptides Lab
Tracked$119.00 / 10mg($119.00 to 10mg)
Checked Aug 15, 2026
Check price at Apex Peptides Lab →Optimum Formula
Tracked$59.99 / 5mg($119.98 to 10mg)
Checked May 14, 2026
Check price at Optimum Formula →Woosh Labs
Tracked$59.99 / 5mg($119.98 to 10mg)
Checked Jun 24, 2026
Check price at Woosh Labs →Evo Labs Research
Tracked$119.99 / 20mg($119.99 to 10mg)
Checked Jun 22, 2026
Check price at Evo Labs Research →BioPure Peptides
Tracked$119.99 / 10mg($119.99 to 10mg)
Checked Jul 27, 2026
Check price at BioPure Peptides →Orbitrex Peptides
Tracked$119.99 / 20mg($119.99 to 10mg)
Checked Aug 3, 2026
Check price at Orbitrex Peptides →Ignite Peptides
Tracked$60.00 / 5mg($120.00 to 10mg)
Checked Jun 12, 2026
Check price at Ignite Peptides →Modern Aminos
Tracked$61.20 / 5mg($122.40 to 10mg)
Checked May 14, 2026
Check price at Modern Aminos →Nationwide Peptides
Tracked$123.00 / 30mg($123.00 to 10mg)
Checked Aug 5, 2026
Check price at Nationwide Peptides →Offline Peptides
Tracked$129.00 / 30mg($129.00 to 10mg)
Checked Jul 28, 2026
Check price at Offline Peptides →CertaPeptides
Tracked$129.86 / 30mg($129.86 to 10mg)
Checked Jun 27, 2026
Check price at CertaPeptides →Evolve Peptides
Tracked$129.90 / 10mg($129.90 to 10mg)
Checked Apr 22, 2026
Check price at Evolve Peptides →LA Peptides
Tracked$64.99 / 5mg($129.98 to 10mg)
Checked May 14, 2026
Check price at LA Peptides →UNYX Peptides
Tracked$129.99 / 20mg($129.99 to 10mg)
Checked Jul 31, 2026
Check price at UNYX Peptides →PureBio Labs
Tracked$129.99 / 10mg($129.99 to 10mg)
Checked Aug 5, 2026
Check price at PureBio Labs →Hydro Research
Tracked$65.00 / 5mg($130.00 to 10mg)
Checked Jun 5, 2026
Check price at Hydro Research →Atomik Labz
Tracked$69.00 / 5mg($138.00 to 10mg)
Checked Aug 4, 2026
Check price at Atomik Labz →Evolve Peptides
Tracked$69.90 / 5mg($139.80 to 10mg)
Checked Apr 22, 2026
Check price at Evolve Peptides →Optima Supply
Tracked$69.99 / 5mg($139.98 to 10mg)
Checked Aug 3, 2026
Check price at Optima Supply →Apex Peptides Lab
Tracked$70.00 / 5mg($140.00 to 10mg)
Checked Aug 15, 2026
Check price at Apex Peptides Lab →Apex Peptides
Tracked$140.00 / 30mg($140.00 to 10mg)
Checked Jul 31, 2026
Check price at Apex Peptides →Atomik Labz
Tracked$149.00 / 30mg($149.00 to 10mg)
Checked Aug 4, 2026
Check price at Atomik Labz →Evo Labs Research
Tracked$149.99 / 30mg($149.99 to 10mg)
Checked Jun 22, 2026
Check price at Evo Labs Research →UNYX Peptides
Tracked$149.99 / 30mg($149.99 to 10mg)
Checked Jul 31, 2026
Check price at UNYX Peptides →Evolve Peptides
Tracked$155.00 / 15mg($155.00 to 10mg)
Checked Apr 22, 2026
Check price at Evolve Peptides →Apex Peptides Lab
Tracked$169.00 / 20mg($169.00 to 10mg)
Checked Aug 15, 2026
Check price at Apex Peptides Lab →Ignite Peptides
Tracked$170.00 / 20mg($170.00 to 10mg)
Checked Jun 12, 2026
Check price at Ignite Peptides →Optimum Formula
Tracked$174.99 / 30mg($174.99 to 10mg)
Checked May 14, 2026
Check price at Optimum Formula →Evolve Peptides
Tracked$39.90 / 2mg($199.50 to 10mg)
Checked Apr 22, 2026
Check price at Evolve Peptides →Evolve Peptides
Tracked$199.90 / 20mg($199.90 to 10mg)
Checked Apr 22, 2026
Check price at Evolve Peptides →Pepsynth Labs
Tracked$220.00 / 10mg($220.00 to 10mg)
Checked Aug 7, 2026
Check price at Pepsynth Labs →Hydro Research
Tracked$325.00 / 25mg($325.00 to 10mg)
Checked Jun 5, 2026
Check price at Hydro Research →Apex Peptides Lab
Tracked$79.00 / 2mg($395.00 to 10mg)
Checked Aug 15, 2026
Check price at Apex Peptides Lab →Pepsynth Labs
Tracked$400.00 / 20mg($400.00 to 10mg)
Checked Aug 7, 2026
Check price at Pepsynth Labs →Hydro Research
Tracked$590.00 / 50mg($590.00 to 10mg)
Checked Jun 5, 2026
Check price at Hydro Research →Hydro Research
Tracked$990.00 / 100mg($990.00 to 10mg)
Checked Jun 5, 2026
Check price at Hydro Research →Puratek Peptides
Tracked$24.95 / 5mg($49.90 to 10mg)
Checked Jul 31, 2026
Check price at Puratek Peptides →Alpha Peptides
Tracked$64.99 / 10mg($64.99 to 10mg)
Checked Jul 31, 2026
Check price at Alpha Peptides →PeakForce Labs
Tracked$89.00 / 15mg($89.00 to 10mg)
Checked Aug 15, 2026
Check price at PeakForce Labs →Alpha Peptides
Tracked$44.99 / 5mg($89.98 to 10mg)
Checked Jul 31, 2026
Check price at Alpha Peptides →Chameleon Peptides
Tracked$49.50 / 5mg($99.00 to 10mg)
Checked Jul 31, 2026
Check price at Chameleon Peptides →UNYX Peptides
Tracked$49.99 / 5mg($99.98 to 10mg)
Checked Jul 31, 2026
Check price at UNYX Peptides →Semaglutide price report
Semaglutide currently costs as little as $20.00 to obtain 10mg, from Red River Peptides. Across the 62 vendors we track, the typical cost to 10mg is $69.00, using each vendor's own cheapest listing. 61 of those vendors show current stock, and prices were checked through Aug 15, 2026.
- Lowest to 10mg
- $20.00
- Red River Peptides
- Median to 10mg
- $69.00
- one offer per vendor
- Lowest package
- $20.00
- 10mg at Red River Peptides
- Vendors tracked
- 62
- 61 in stock
Checked through Aug 15, 2026. Prices are aggregated from public vendor listings. Sources and data licensing are documented on our methodology page.
At a glance
- Category
- fat loss
- Mechanism class
- GLP-1 / GIP agonist
- Research phase
- FDA approved (for specific indications)
- NCAA status
- Not explicitly listed (catchall risk) — GLP-1 agonist. On WADA 2026 Monitoring Program (in- and out-of-competition) but NOT prohibited. NCAA mirrors — no explicit listing.
- WADA status
- Not currently prohibited (monitor WADA list)
Overview
Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist developed by Novo Nordisk, originally for type 2 diabetes management and later approved for chronic weight management. It is administered by subcutaneous injection (Ozempic, Wegovy) or as a daily oral tablet (Rybelsus, and more recently an oral Wegovy formulation).
GLP-1 receptor agonist
Research timeline
2017
FDA approved Ozempic (semaglutide injection) for type 2 diabetes based on the SUSTAIN trial program.
Source →2019
FDA approved Rybelsus, the first oral GLP-1 receptor agonist, for type 2 diabetes.
Source →2021
FDA approved Wegovy for chronic weight management based on the STEP Phase 3 trial program (STEP 1-4, >4,500 participants); STEP-1 reported 14.9% mean weight loss at 68 weeks vs 2.4% placebo.
Source →2022
Wegovy approval extended to adolescents aged 12 and older.
Source →2024
Wegovy approved for cardiovascular risk reduction in adults with overweight/obesity and established cardiovascular disease, based on the SELECT trial (17,604 participants).
Source →2025
Ozempic approved to reduce risk of worsening kidney disease and cardiovascular death in adults with type 2 diabetes and chronic kidney disease; FDA also approved an oral Wegovy tablet based on the Phase III OASIS 4 trial (NCT05564117).
Source →
Active & recent research
OASIS 4 (oral semaglutide for weight loss)
efficacy and safety of a 25 mg oral semaglutide tablet for weight management
SELECT cardiovascular outcomes trial
cardiovascular death, nonfatal MI, and nonfatal stroke in adults with obesity/overweight and established cardiovascular disease
Wegovy MASH indication trials
improvement of metabolic dysfunction-associated steatohepatitis (MASH) and liver fibrosis
Key findings
- STEP-1 (Phase 3, N=1,961) reported 14.9% mean body weight loss at 68 weeks with semaglutide 2.4 mg versus 2.4% with placebo.
- SUSTAIN 6, a cardiovascular outcomes trial, reported a significant reduction in major adverse cardiovascular events versus placebo (HR 0.74) over a median follow-up of 2.1 years.
- The SELECT trial (17,604 participants) established cardiovascular risk reduction in adults with overweight/obesity and established cardiovascular disease, supporting a 2024 label expansion.
- OASIS 4 reported 16.6% mean weight loss at 64 weeks with full adherence to oral semaglutide 25 mg, versus 2.7% for placebo.
Safety & regulatory notes
Brand-name semaglutide (Ozempic, Wegovy, Rybelsus) is FDA-approved with an established label including boxed warnings and known GI-related adverse effects. The FDA has separately issued repeated public warnings about compounded (non-brand) semaglutide: as of mid-2025 the agency proposed permanently excluding semaglutide from the list of bulk substances 503A/503B compounders may use, and by July 2025 had received over 1,150 adverse event reports tied to compounded semaglutide and tirzepatide, many linked to dosing errors, product quality issues, and in some cases fraudulent labeling.
We may earn a commission when readers buy through links on this page, at no extra cost to you. Commissions never affect a vendor's score. Every vendor is graded on the same public rubric built from published lab documentation, live catalog pricing, and community sentiment. How we score →
Where it's sold for research
We haven't built a dedicated vendor-availability page for Semaglutide yet. See our full research-peptide vendor rankings →
Semaglutide FAQ
Is semaglutide FDA-approved?+
Yes, under three brand names: Ozempic and Rybelsus for type 2 diabetes (with additional cardiovascular/kidney indications for Ozempic), and Wegovy for chronic weight management and cardiovascular risk reduction.
What is semaglutide studied for?+
Approved and ongoing research covers type 2 diabetes glycemic control, chronic weight management, cardiovascular risk reduction, chronic kidney disease progression, and MASH (fatty liver disease).
Is compounded semaglutide legal and safe?+
The FDA has stated compounded semaglutide is an unapproved product that has not undergone its review for safety, effectiveness, and quality, and has documented adverse events including dosing errors and fraudulent labeling; the agency moved in 2025 to restrict compounding of semaglutide by 503A/503B facilities.
Is semaglutide the same as research-grade semaglutide sold online?+
No. FDA-approved semaglutide is manufactured, tested, and dispensed under strict pharmaceutical regulation; 'research chemical' semaglutide sold outside that system has not been reviewed by the FDA for identity, purity, or safety.
Sources for this page (6)
- 1 https://www.ncbi.nlm.nih.gov/books/NBK603723/
- 2 https://www.drugs.com/history/wegovy.html
- 3 https://www.ajmc.com/view/fda-approves-oral-semaglutide-as-first-glp-1-pill-for-weight-loss
- 4 https://www.appliedclinicaltrialsonline.com/view/fda-approves-oral-wegovy-positive-oasis-trial-results
- 5 https://healthrx.com/regulatory-wegovy/fda-approval-history
- 6 https://www.fda.gov/drugs/drug-alerts-and-statements/fdas-concerns-unapproved-glp-1-drugs-used-weight-loss
Researched together
Related: all compound research overviews · full price index · research radar · full vendor rankings · methodology