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Cagrilintide: Research Overview & Current Status

In clinical trials

Cagrilintide is a long-acting amylin analog. Current research status: in clinical trials. Cagrilintide is not FDA-approved as a standalone drug; the CagriSema combination (cagrilintide + semaglutide) had a New Drug Application submitted to the FDA in December 2025, with approval anticipated in late 2026 per industry trackers, but as of this review it remains unapproved.

Live vendor pricing

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Anglo Peptides

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$57.08 / 10mg($57.08 to 10mg)

Checked Jul 19, 2026

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Promino

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$59.99 / 10mg($59.99 to 10mg)

Checked Jul 17, 2026

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Step One Ventures

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$63.00 / 10mg($63.00 to 10mg)

Checked Jul 22, 2026

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Elite Edge Biotech

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$63.00 / 10mg($63.00 to 10mg)

Checked Jul 28, 2026

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Premier Research

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$65.00 / 10mg($65.00 to 10mg)

Checked Jul 20, 2026

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NextGen Peptides

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$65.00 / 10mg($65.00 to 10mg)

Checked Jul 24, 2026

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NexPept

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$67.40 / 10mg($67.40 to 10mg)

Checked Jul 22, 2026

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Woosh Labs

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$69.00 / 10mg($69.00 to 10mg)

Checked Jun 24, 2026

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Amino Club

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$69.99 / 10mg($69.99 to 10mg)

Checked Aug 7, 2026

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MsAmino

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$69.99 / 10mg($69.99 to 10mg)

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Step One Ventures

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$35.00 / 5mg($70.00 to 10mg)

Checked Jul 22, 2026

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Anglo Peptides

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$36.39 / 5mg($72.78 to 10mg)

Checked Jul 19, 2026

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Puratek Peptides

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$72.95 / 10mg($72.95 to 10mg)

Checked Jul 31, 2026

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Badger Compounds

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$73.99 / 10mg($73.99 to 10mg)

Checked Aug 15, 2026

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Avara

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$75.00 / 10mg($75.00 to 10mg)

Checked Aug 7, 2026

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Evo Labs Research

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$79.99 / 10mg($79.99 to 10mg)

Checked Jun 22, 2026

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Amino Science Labs

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$79.99 / 10mg($79.99 to 10mg)

Checked Jul 27, 2026

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Premier Research

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$40.00 / 5mg($80.00 to 10mg)

Checked Jul 20, 2026

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NextGen Peptides

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$40.00 / 5mg($80.00 to 10mg)

Checked Jul 24, 2026

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EZ Peptides

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$44.00 / 5mg($88.00 to 10mg)

Checked Aug 13, 2026

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EZ Peptides

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$88.00 / 10mg($88.00 to 10mg)

Checked Aug 13, 2026

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Midwest Peptide

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$89.99 / 10mg($89.99 to 10mg)

Checked Jun 18, 2026

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Axon Chems

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$90.00 / 10mg($90.00 to 10mg)

Checked Jul 31, 2026

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Refined BioLabs

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$90.00 / 10mg($90.00 to 10mg)

Checked Jul 30, 2026

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Puratek Peptides

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$45.95 / 5mg($91.90 to 10mg)

Checked Jul 31, 2026

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Peptide Giants

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$49.49 / 5mg($98.98 to 10mg)

Checked Aug 1, 2026

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Peptide Giants

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$98.99 / 10mg($98.99 to 10mg)

Checked Aug 1, 2026

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Offline Peptides

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$99.00 / 10mg($99.00 to 10mg)

Checked Jul 28, 2026

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Optimum Formula

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$49.99 / 5mg($99.98 to 10mg)

Checked May 14, 2026

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LA Peptides

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$99.99 / 10mg($99.99 to 10mg)

Checked May 14, 2026

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Orbitrex Peptides

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$99.99 / 10mg($99.99 to 10mg)

Checked Aug 3, 2026

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Rivn Peptides

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$99.99 / 10mg($99.99 to 10mg)

Checked Aug 14, 2026

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Red River Peptides

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$50.00 / 5mg($100.00 to 10mg)

Checked May 19, 2026

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PeakForm Peptides

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$100.00 / 10mg($100.00 to 10mg)

Checked Aug 1, 2026

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Glacier Aminos

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$101.99 / 10mg($101.99 to 10mg)

Checked Jul 31, 2026

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Axon Chems

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$55.00 / 5mg($110.00 to 10mg)

Checked Jul 31, 2026

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Onyx Research

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$110.00 / 10mg($110.00 to 10mg)

Checked Apr 6, 2026

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Pantheon Peptides

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$111.60 / 10mg($111.60 to 10mg)

Checked Apr 23, 2026

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CertaPeptides

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$113.34 / 10mg($113.34 to 10mg)

Checked Jun 27, 2026

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Glacier Aminos

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$56.99 / 5mg($113.98 to 10mg)

Checked Jul 31, 2026

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PeakForce Labs

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$59.00 / 5mg($118.00 to 10mg)

Checked Aug 15, 2026

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Peptira

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$119.00 / 10mg($119.00 to 10mg)

Checked May 14, 2026

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SomaChems

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$59.99 / 5mg($119.98 to 10mg)

Checked May 14, 2026

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MsAmino

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$59.99 / 5mg($119.98 to 10mg)

Checked Aug 15, 2026

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SKO Compounds

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$119.99 / 10mg($119.99 to 10mg)

Checked Jul 23, 2026

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Mile High Compounds

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$119.99 / 10mg($119.99 to 10mg)

Checked Aug 3, 2026

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PeakForm Peptides

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$60.00 / 5mg($120.00 to 10mg)

Checked Aug 1, 2026

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Licensed Peptides

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$122.99 / 10mg($122.99 to 10mg)

Checked Jun 4, 2026

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GLP-1 Research Lab

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$62.50 / 5mg($125.00 to 10mg)

Checked Jun 19, 2026

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Nationwide Peptides

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$127.00 / 10mg($127.00 to 10mg)

Checked Aug 5, 2026

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NeuroLabs

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$64.95 / 5mg($129.90 to 10mg)

Checked Jul 31, 2026

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Vantyx Research

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$65.00 / 5mg($130.00 to 10mg)

Checked Aug 15, 2026

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Offline Peptides

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$65.00 / 5mg($130.00 to 10mg)

Checked Jul 28, 2026

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VoidResearch

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$65.00 / 5mg($130.00 to 10mg)

Checked Jul 30, 2026

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Nationwide Peptides

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$65.00 / 5mg($130.00 to 10mg)

Checked Aug 5, 2026

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Modern Aminos

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$134.00 / 10mg($134.00 to 10mg)

Checked May 14, 2026

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Pristine Aminos

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$135.00 / 10mg($135.00 to 10mg)

Checked Aug 2, 2026

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Arizen Bio Labs

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$69.99 / 5mg($139.98 to 10mg)

Checked Jun 21, 2026

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Apex Peptides

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$140.00 / 10mg($140.00 to 10mg)

Checked Jul 31, 2026

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Evolve Peptides

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$150.00 / 10mg($150.00 to 10mg)

Checked Apr 22, 2026

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Pepsynth Labs

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$150.00 / 10mg($150.00 to 10mg)

Checked Aug 7, 2026

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CertaPeptides

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$75.18 / 5mg($150.36 to 10mg)

Checked Jun 27, 2026

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Pantheon Peptides

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$75.60 / 5mg($151.20 to 10mg)

Checked Apr 23, 2026

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Swift Peptides

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$164.99 / 10mg($164.99 to 10mg)

Checked Aug 6, 2026

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Atomik Labz

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$170.00 / 10mg($170.00 to 10mg)

Checked Aug 4, 2026

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PureBio Labs

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$170.00 / 10mg($170.00 to 10mg)

Checked Aug 5, 2026

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Evolve Peptides

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In stock

$90.00 / 5mg($180.00 to 10mg)

Checked Apr 22, 2026

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Atomik Labz

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$90.00 / 5mg($180.00 to 10mg)

Checked Aug 4, 2026

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Novatherix Laboratories

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$99.99 / 5mg($199.98 to 10mg)

Checked Jun 4, 2026

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Optima Supply

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$100.00 / 5mg($200.00 to 10mg)

Checked Aug 3, 2026

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CertaPeptides

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$202.20 / 20mg($202.20 to 10mg)

Checked Jun 27, 2026

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Licensed Peptides

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$107.99 / 5mg($215.98 to 10mg)

Checked Jun 4, 2026

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Hydro Research

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$110.00 / 5mg($220.00 to 10mg)

Checked Jun 5, 2026

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BioLongevity Labs

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$170.00 / 5mg($340.00 to 10mg)

Checked Aug 2, 2026

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Alpha Peptides

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$95.99 / 10mg($95.99 to 10mg)

Checked Jul 31, 2026

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Ascend Amino

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Out of stock

$55.00 / 5mg($110.00 to 10mg)

Checked Jul 28, 2026

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Alpha Peptides

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Out of stock

$56.99 / 5mg($113.98 to 10mg)

Checked Jul 31, 2026

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NextGen Peptides

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Out of stock

$300.00 / 50mg($300.00 to 10mg)

Checked Jul 24, 2026

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NextGen Peptides

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Out of stock

$480.00 / 100mg($480.00 to 10mg)

Checked Jul 24, 2026

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Cagrilintide price report

Cagrilintide currently costs as little as $57.08 to obtain 10mg, from Anglo Peptides. Across the 57 vendors we track, the typical cost to 10mg is $101.99, using each vendor's own cheapest listing. 55 of those vendors show current stock, and prices were checked through Aug 15, 2026.

Lowest to 10mg
$57.08
Anglo Peptides
Median to 10mg
$101.99
one offer per vendor
Lowest package
$35.00
5mg at Step One Ventures
Vendors tracked
57
55 in stock

Checked through Aug 15, 2026. Prices are aggregated from public vendor listings. Sources and data licensing are documented on our methodology page.

At a glance

Category
fat loss
Mechanism class
GLP-1 / GIP agonist
Research phase
Research / preclinical only
NCAA status
Not explicitly listed (catchall risk) — Long-acting amylin analog. Not on NCAA or WADA prohibited list.
WADA status
Not currently prohibited (monitor WADA list)

Overview

Cagrilintide is a long-acting, stable synthetic analog of amylin, a pancreatic hormone involved in satiety and glucose regulation, developed by Novo Nordisk. It is under investigation both alone and as a fixed-dose combination with semaglutide (marketed name CagriSema) for obesity and type 2 diabetes.

long-acting amylin analog

Research timeline

  1. 2020s

    Cagrilintide entered clinical development as a long-acting amylin analog, initially studied as monotherapy and later as a fixed-dose combination with semaglutide (CagriSema).

    Source →
  2. 2025

    REDEFINE 1, a 68-week Phase 3 trial in 3,417 adults with obesity/overweight, compared CagriSema against cagrilintide monotherapy, semaglutide monotherapy, and placebo; results presented at the 85th ADA Scientific Sessions reported more than 1 in 5 participants losing 30%+ body weight with CagriSema.

    Source →
  3. 2025

    REIMAGINE 2, a Phase 3 trial in 2,713 randomized participants with type 2 diabetes, reported significantly greater HbA1c reduction with cagrilintide-semaglutide versus semaglutide alone.

    Source →
  4. 2025

    Novo Nordisk submitted a New Drug Application to the FDA for CagriSema for weight management.

    Source →

Active & recent research

Phase 3 (ongoing)

REDEFINE 4

head-to-head comparison of CagriSema against tirzepatide (Zepbound/Mounjaro)

Phase 3

REIMAGINE program

cagrilintide-semaglutide combination for type 2 diabetes across multiple trials

preclinical/mechanistic

Cagrilintide mechanism research

role of brain amylin receptors 1 and 3 in cagrilintide-induced body weight reduction

Key findings

  • REDEFINE 1 (N=3,417) reported that adults taking CagriSema lost an average of 23% body weight under the treatment-effect (on-treatment) analysis at 68 weeks.
  • REIMAGINE 2 reported a mean HbA1c change of -1.91 percentage points with cagrilintide-semaglutide versus -1.75 with semaglutide alone (estimated treatment difference -0.16, p=0.0035).
  • Preclinical mechanistic research reported that cagrilintide lowers body weight via brain amylin receptors 1 and 3.
  • Across REDEFINE and REIMAGINE trials, the most common adverse events were gastrointestinal and reported as mostly mild to moderate, diminishing over time, consistent with incretin/amylin-class therapies.

Safety & regulatory notes

Cagrilintide and the CagriSema combination remain investigational; neither is FDA-approved as of this review, though an NDA for CagriSema was submitted in December 2025. Reported adverse events in Phase 3 trials have been predominantly gastrointestinal, similar to other amylin- and GLP-1-based therapies. As an unapproved compound, any cagrilintide sold outside Novo Nordisk's clinical trial program is an unregulated research chemical with unverified purity and no established human safety data outside trial settings.

How this site makes money

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Where it's sold for research

We haven't built a dedicated vendor-availability page for Cagrilintide yet. See our full research-peptide vendor rankings →

Cagrilintide FAQ

Is cagrilintide FDA-approved?+

No. Cagrilintide and the CagriSema combination remain investigational; a New Drug Application for CagriSema was submitted to the FDA in December 2025 with a potential approval decision anticipated in late 2026.

What is cagrilintide studied for?+

Phase 3 trials (REDEFINE and REIMAGINE programs) are studying cagrilintide, both alone and combined with semaglutide, for obesity/overweight and type 2 diabetes management.

Is cagrilintide legal to buy for research purposes?+

It is sold by some vendors as a research chemical labeled not for human use; because it remains investigational and unapproved, purity, dosing accuracy, and safety outside Novo Nordisk's clinical trials are not verified.

How is cagrilintide different from semaglutide?+

Cagrilintide is an amylin analog rather than a GLP-1 receptor agonist; it is being developed as a fixed-dose combination with semaglutide (CagriSema) to target complementary satiety and glucose-regulation pathways.

Sources for this page (5)

  1. 1 https://www.prnewswire.com/news-releases/novo-nordisk-files-for-fda-approval-of-cagrisema-the-first-once-weekly-combination-of-glp1-and-amylin-analogues-for-weight-management-302645862.html
  2. 2 https://www.adameetingnews.org/redefine-trials-advance-cagrilintide-semaglutide-combination-treatment-for-weight-management/
  3. 3 https://pubmed.ncbi.nlm.nih.gov/42251859/
  4. 4 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12270663/
  5. 5 https://bodevolvebariatric.com/cagrisema/

Researched together

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